Laboratory evaluation of a novel microfluidic nanoparticle-based immunoassay` for the detection of dengue virus NS1 antigen in a dengue-endemic setting

Abstract: Serological diagnosis of dengue fever is based on the detection of NS1 antigen and further confirmed
by the assay of dengue IgM and IgG. Rapid Diagnostic Tests (RDTs) are no longer recommended for use by the
Government of India. However, there is a requirement of rapid results without compromising on the test quality.
Accordingly, we undertook an evaluation of a novel cartridge-based system employing a unique table-top diagnostic
device for dengue NS1 antigen by BluSense Diagnostics incorporating a patented Immuno-Magnetic Assay (IMA).